How to force delete a file!

Remember the location of the file, reboot into safe mode to delete, enter the safe mode method: at boot time,press F8. I believe we all come across to delete a file, the message "The file is in use by another process can not be deleted", and the usual method is to close the program using the file or the Task Manager to kill the relevant process , delete. If you can not be deleted, then you can try the following method:
(1) log off or restart, then delete it.
(2) into safe mode or boot floppy disk (CD) to boot into pure DOS or a CD or flash drive into the system winpe, delete.
(3) If the folder is deleted, the first to enter the folder, delete all the contents inside, and then return to the parent directory, delete the folder.
(4) Use optimization software.